By J.W. Gorrod, P. Jacob III
This ebook presents for the 1st time a unmarried complete resource of data at the analytical chemistry of nicotine and similar alkaloids. The editors have introduced jointly scientists from academia and the tobacco to explain the cutting-edge of the chemistry and analytical tools for dimension of nicotine. either the scope and element of the e-book are amazing. Chapters describe the background, pharmacology and toxicology of nicotine, the biosynthesis of nicotine and different alkaloids within the tobacco plant, the overall chemistry of nicotine and the analytical methodologies which were used to degree nicotine and similar alkaloids in organic specimens, in tobacco and pharmaceutical items and in tobacco smoke. there's additionally a complete evaluation of the chemistry and toxicology of nicotine-derived nitrosamines, an enormous category of tobacco cancer agents.
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This publication offers for the 1st time a unmarried entire resource of knowledge at the analytical chemistry of nicotine and similar alkaloids. The editors have introduced jointly scientists from academia and the tobacco to explain the cutting-edge of the chemistry and analytical tools for dimension of nicotine.
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Additional resources for Analytical Determination of Nicotine and Related Compounds and their Metabolites
90 Baldwin IT, Gorham D, Schmelz EA, Lewandowski CA, Lynds GY. Allocation of nitrogen to an inducible defense and seed production in Nicotiana attenuata. Oecologia, 1998: 115; 541-552. 91 Lynds GY, Baldwin IT. Fire, nitrogen, and defensive plasticity in Nicotiana attenuata. Oecologia, 1998: 115; 531-540. 92 Baldwin IT, Karb MJ, Ohnmeiss TE. Allocation of 15N from nitrate to nicotine: production and turnover of a damage-induced mobile defense. Ecology, 1994: 75; 1703-1713. 93 Ohnmeiss TE, Baldwin IT.
Expression of the rolC gene and nicotine production in transgenic roots and their regenerated plants. , 1998: 17; 384-390. , Roguchi M. and Tamaki E. Changes in the activities of ornithine decarboxylase, putrescine N-methyltransferase and N-methylputrescine oxidase in tobacco roots in relation to nicotine biosynthesis. , 1973: 14; 103-110. 78 Takahashi M, Yamada Y. Regulation of nicotine production by auxins in tobacco cultured cells in vitro. Agric. Biol. , 1973: 37; 1755-1757. 79 Tiburcio AF, Kaur-Sawhney R, Ingersoll RB, Galston AW.
Compared with leaves damaged by microscissors, leaves damaged by caterpillars produced twice as much JA per cm of cut edge in the damaged area. Despite the difference in JA production, amounts of nicotine in plants damaged by the two methods did not differ. Moreover, and in line with the nicotine findings, although JA in roots was increased by both kinds of damage, its level did not differ between the two treatments. The role played by caterpillar regurgitant (insect herbivore regurgitants are known to trigger release of volatile compounds when applied to damaged plant surfaces) in the JA and alkaloidal responses was tested by applying distilled water or a regurgitant preparation to leaves on separate plants that had been damaged in a standardized manner using a fabric pattern wheel.